This is dog Latin for "out of many come smartasses" (or "a smartass"). It's modelled off the phrase ē pluribus unum, "out of many [comes] one", which is printed on American currency, plus the fake Latin smart-assimus for "smartasses".
What does the saying E Pluribus Unum mean?
"E Pluribus Unum" was the motto proposed for the first Great Seal of the United States by John Adams, Benjamin Franklin, and Thomas Jefferson in 1776. A latin phrase meaning "One from many," the phrase offered a strong statement of the American determination to form a single nation from a collection of states.
What is the meaning of out of many one?
The motto refers to the emergence of a single nation out of the union of the 13 original colonies, and is emblazoned across the Great Seal of the United States.